Unlock the Secrets of Healthy Blood
Erythropoiesis: The Complex Process of Red Blood Cell Production
Erythropoiesis, or as we like to call it 'the red blood cell production process' is quite a complex process that involves a lot of stages, sites, and regulators. In this article we'll try to break it down for you as it's good to know if you want to stay fit, healthy and energised.
So, our bodies have these little stem cells called haemocytoblasts. Well, these guys are like the superheroes of our blood production system because they have the power to differentiate into common myeloid progenitor cells (blood stem cells), which eventually become fully mature red blood cells. And this magic happens mostly in the bone marrow of vertebrae, ribs, sternum, sacrum, pelvis, and femur. Yes we know, it sounds like a lot of places, but trust us, it's all in the name of creating those beautiful, oxygen-carrying red blood cells that give us the energy we need to thrive.
Speaking of oxygen, it's kind of a big deal. That's why our bodies have this hormone called erythropoietin (EPO), which is secreted by the kidneys. When there's a drop in oxygen levels in our bodies, EPO production kicks into high gear, leading to an increase in red blood cell production. It's like our bodies are saying, "Hey, we need more oxygen carriers!" And then our blood production system goes, "Got it, boss!" It's a pretty neat system if you ask us.
But, as with all systems, things can go awry. When there's a deviation from the normal process of erythropoiesis, it can lead to disorders like constant fatigue and anaemia. Anaemia is caused by a decrease in red blood cell production or increased red cell removal (more on this in another article).
The Surprising Importance of Nutrients for Red Blood Cell Production
To make sure everything stays on track, we need to get our nutrients in check. Vitamin B12, folate and iron are essential for adequate erythropoiesis for the following reasons:
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Vitamin B12 plays a crucial role in the production of red blood cells by aiding in the maturation process of red blood cells. Without sufficient amounts of B12, red blood cells become abnormally large and ineffective, leading to megaloblastic anemia. B12 also helps maintain the health of nerve cells and plays a role in DNA synthesis.
- Folate (B9) is essential for erythropoiesis, the process of red blood cell production, because it is required for DNA synthesis and cell division. Without sufficient folate, red blood cells may not divide properly and their production may be decreased, leading to megaloblastic anaemia.
- Iron is essential for red blood cell production because it is a critical component of hemoglobin, the protein that allows red blood cells to transport oxygen throughout the body. Without adequate iron, the body cannot produce enough healthy red blood cells, again leading to anemia.
How Can Beef Liver & Organs Support Erythropoiesis?
Many people assume that beef organs are simply a good source of iron which in turn helps to fight fatigue. While they do contain heme iron they are particularly rich in vitamin A and B-vitamins, and are also rich in minerals, including magnesium and zinc. These are the building blocks required to support healthy red blood cell production. They also come packed as nature intended in a whole food animal-based source that are generally more bioavailable than plant-based or synthetic supplements.
